Gratitude may help you handle pain, new study suggests
NCT ID NCT06317844
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a short gratitude exercise can change how people experience pain. 145 healthy adults did a cold water hand test to measure pain. Researchers also checked if certain genes affect the results. The goal was to learn more about how thoughts and biology work together in pain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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145 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * must be pain-free * must be at least 18 years old Exclusion Criteria: * cardiovascular disease * Raynaud's disease * epilepsy * being pregnant * having a current injury to or open cut or sore on one's non-dominant hand * history of fainting or seizures * history of frostbite in non-dominant hand * chronic pain conditions (e.g., fibromyalgia, neuropathy, arthritis) * diabetes * malignant tumor * chronic lung disease * liver disease * kidney disease * gastrointestinal diseases * currently taking opioids
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Black Hills State University
Spearfish, South Dakota, 57799, United States
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Other studies related to the condition(s) this trial covers.
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