Grape study seeks to strengthen muscles and minds in women over 65
NCT ID NCT07208916
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether eating grapes can help improve muscle strength and thinking skills in healthy women aged 65 and older. Participants will attend four sessions for muscle tests, cognitive tests, and blood draws. The goal is to see if a simple dietary change can support healthy aging.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 35 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Apr 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy female (confirmed by medical history) * Aged 65 or older; * Able to walk household distances without assistance from another person * Non-smoker; * Dominant hand grip strength at or below normal value for age and gender; * Had not consumed recreational drugs for one week prior; * Agreed not to participate in any clinical or patch test studies at Day 1 through study completion; * Completed a medical intake; * Read, understood, and signed an informed consent. Exclusion Criteria: * Using nasally inhaled/systemic/topical corticosteroids within 4 weeks prior to and/or during the study, or systemic/topical antihistamines 72 hours prior to and during the study; * Using certain antifungal drugs, antihistamines (including diphenhydramine, or Benadryl), antibiotics 4 (including "sulfa" drugs, quinolones and tetracyclines), oral diabetes drugs, sulfonylureas, diuretics, and tricyclic antidepressants. Some herbal supplements such as St. John's Wort would make a person ineligible; * Not willing to refrain from using acetaminophen (occasional use permitted, except within 48 hours of a study visit) or systemic/topical anti-inflammatory analgesics such as aspirin, Aleve, Motrin, Advil, Orudis, or Nuprin for 72 hours prior to and during study visits; * Any of the following in the 4 weeks prior to start of study: 1. Major surgery for any indication 2. On cytotoxic chemotherapy for any indication (including methotrexate for arthritis) 3. Hormonal therapy for cancer prevention (including tamoxifen). Note: treatment with finasteride/dutasteride for BPH does not render a participant ineligible 4. Using medication which, in the opinion of the Investigator, would interfere with the study results (e.g., anti-inflammatory medications, antipsychotics, anticonvulsants with potential pain relief effects, immunomodulatory medications; blood thinners); * Known sensitivity or allergy to grape powder; * Nut allergies; * Had received treatment for any type of internal cancer within 5 years prior to study entry; * Had a history of or currently being treated for: 1. Hepatitis; 2. Diabetes (including insulin injections); 3. Solid organ or bone marrow transplant 4. Keloid formation 5. Chronic renal or hepatic disorder 6. Significant bleeding disorder 7. Progressive neurodegenerative condition 8. Swallowing disorder * OTHER a. Any condition that might have compromised study results; * Uncontrolled concurrent illness including ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, uncontrolled symptomatic cardiac arrhythmia, psychiatric illness/social situations that limited compliance with study requirements or other underlying serious medical condition which, in the investigator's opinion precluded study participation. b. Currently participating in any clinical testing; c. Received any investigational drug(s) within 28 days from Day 1. Participants must also follow the following Subject Responsibilities: Participants are not to consume the following foods during the study: Artichokes, figs, green tea, almonds, red fruits and vegetables, turmeric, olive oil, berries (blueberries, blackberries, grapes, raspberries, strawberries, goji berries, etc.), cocoa, dark chocolate, pomegranate, red wine Participants are to limit the following foods during the study: Coffee/Tea - 1X per day, beans/legumes - 2X per week, Soy foods (tofu, soy milk, miso, tempeh) 2X per week Participants are not to consume the following supplements during the study: Multivitamin, Alpha lipoic acid, B vitamins, Coenzyme Q10, Elderberry, Ellagic acid, Fish oil, Flaxseed or flaxseed oil, Grapeseed extract, Green tea, Lycopene 6, Niacinamide, Quercetin, Resveratrol, Selenium, Turmeric, Vitamin C, E, K
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Western New England University
RECRUITINGSpringfield, Massachusetts, 01119, United States
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