Dental bone graft showdown: your own bone vs donor bone
NCT ID NCT07412067
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using a donor bone graft (allograft) works as well as using your own bone (autograft) to repair defects where a tooth infection has damaged the surrounding bone. Fifty adults with these defects will receive one of the two grafts along with a collagen membrane during dental surgery. Healing will be tracked with 3D X-rays over a year to see which approach leads to better bone regrowth.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bone graft (autograft or allograft) with collagen membrane
- What this could lead to
- If successful, this could show that allografts work as well as autografts for healing these dental defects, offering a less invasive option.
- What could go wrong
- This is a small, early-stage trial with only 50 patients, so results may not apply widely. The procedure is surgical and carries risks like infection or graft failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients aged ≥18 years. Presence of chronic suppurative apical periodontitis with an apicomarginal defect and deep periodontal pocket, suggesting endodontic-periodontal communication up to the apex. Negative response to pulp vitality tests. Exclusion Criteria: Presence of root fractures or perforations. Patients with compromised systemic health (ASA II or above). Smokers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Post Graduate Institute of Dental Sciences, Rohtak
Rohtak, Haryana, 124001, India