Dental bone graft showdown: your own bone vs donor bone

NCT ID NCT07412067

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a donor bone graft (allograft) works as well as using your own bone (autograft) to repair defects where a tooth infection has damaged the surrounding bone. Fifty adults with these defects will receive one of the two grafts along with a collagen membrane during dental surgery. Healing will be tracked with 3D X-rays over a year to see which approach leads to better bone regrowth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bone graft (autograft or allograft) with collagen membrane
What this could lead to
If successful, this could show that allografts work as well as autografts for healing these dental defects, offering a less invasive option.
What could go wrong
This is a small, early-stage trial with only 50 patients, so results may not apply widely. The procedure is surgical and carries risks like infection or graft failure.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Post Graduate Institute of Dental Sciences, Rohtak

    Rohtak, Haryana, 124001, India