Think your way to stronger ankles? new study tests brain training for injury recovery
NCT ID NCT07376915
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether a mental exercise program called Graded Motor Imagery can help people with chronic ankle instability. Over six days, participants will practice ankle recognition tasks, imagine moving their ankle, and use mirror therapy. The study compares results between 48 people with unstable ankles and healthy controls to see if these mental techniques improve pain, stiffness, strength, and balance.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- graded motor imagery (mental exercises including laterality training, motor imagery, and mirror therapy)
- What this could lead to
- If it works, this could offer a simple, drug-free way to improve ankle stability and reduce pain for people with chronic ankle instability.
- What could go wrong
- This is a very small pilot study with only 48 participants, so results may not apply widely. The intervention is mental practice, which may not produce strong physical changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged between 18 and 40 years. * Diagnosed with chronic ankle instability (CAIT ≤ 24). * History of an acute ankle sprain occurring more than 3 months prior to enrollment. * Has not received ankle rehabilitation treatment. * Voluntarily participated in this study Exclusion Criteria: * Vestibular or neurological disorders * Other lower extremity injuries * History of surgery
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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İstanbul Üniversitesi-Cerrahpaşa
RECRUITINGIstanbul, Turkey (Türkiye)
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