Could a daily goji berry mug cake ease menopause symptoms?
NCT ID NCT07660315
First seen Jun 27, 2026 · Last updated Aug 19, 2026 · Updated 4 times
Summary
This pilot study compares two forms of goji berry powder—whole berry and juice powder—in women aged 40 to 65 who have frequent hot flashes. Participants eat one mug cake made with their assigned powder daily for 30 days and track their symptoms on a smartphone. The study looks at changes in HDL cholesterol function, hot flash burden, and cognitive performance to see which form is more promising for future research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- goji berry powder (whole and juice forms)
- What this could lead to
- If successful, this could point toward a dietary supplement that eases hot flashes and supports heart and brain health during menopause.
- What could go wrong
- This is a very small pilot study with only 6 participants, so results may not apply broadly. The effects may be modest or not statistically significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 6 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult women aged 40-65 years * Peri- or postmenopausal with vasomotor symptoms (hot flashes) occurring ≥4 days/week over the past 2 weeks * Willing to consume one mug-cake daily for 30 days * Willing to complete daily VMS symptom tracking on a smartphone * Hormone therapy (HRT) is allowed if the dose has been stable for ≥8 weeks and hot flashes are still present Exclusion Criteria: * Combined intake of \>5 servings of eggs or lutein/zeaxanthin-rich vegetables per week * Current pregnancy or breastfeeding * Known allergy or intolerance to goji (Lycium barbarum) or to key mug-cake ingredients (e.g., wheat/gluten, dairy, and eggs) * Current use of warfarin (goji has reported interactions with anticoagulants); other anticoagulants will be reviewed case-by-case * Uncontrolled thyroid disease or other medical conditions likely to confound VMS assessment * Initiation or planned change of HRT, GLP-1 agonists, or other medications known to affect lipid metabolism or VMS during the 30-day study * Current participation in another interventional study * Any condition that, in the judgment of investigators, makes participation unsafe or data interpretation unreliable
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ragle Human Nutrition Research Center
Davis, California, 95616, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New hope for men battling hot flashes from prostate cancer treatment
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