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New antibody weapon targets Hard-to-Treat blood cancers

NCT ID NCT04606433

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 27 times

Summary

This early-stage study tests a new drug called GNC-038, a quad-specific antibody designed to attack cancer cells in multiple ways. It is for people with certain blood cancers (non-Hodgkin's lymphoma or acute lymphoblastic leukemia) that have come back or not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, and see how the body processes it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, China

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, China

  • Hematology Hospital, Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, 300000, China

  • Nanfang Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, China

  • Shanghai Tongji Hospital

    Shanghai, Shanghai Municipality, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

  • The Second Hospital of Anhui Medical University

    Hefei, Anhui, China

  • Xiangya Hospital Central South University

    Changsha, Hunan, China

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia metastatic malignant neoplasm non-Hodgkin lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.