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New gel may speed up skin healing after laser for acne scars

NCT ID NCT07305675

Symptom relief Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gel containing rhGM-CSF can help skin heal faster after laser treatment for atrophic acne scars. Thirty people with similar scars on both sides of their face received laser treatment on both sides, then applied the gel to one side and a placebo to the other for a week. Researchers measured redness, pigmentation, and overall scar improvement to see if the gel made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) gel
What this could lead to
If it works, this could offer a simple way to speed up healing and reduce redness after laser treatment for acne scars.
What could go wrong
This is a small, early study with only 30 people. Results may not apply to everyone, and the gel might not improve healing significantly over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with atrophic acne scars with essentially symmetric bilateral facial lesion areas, and a Global Scarring Severity (GSS) scale score of Grade 2 or 3 (qualitative assessment); * Patients with normal cognitive function and mental status; * Patients with adequate communication ability; * Patients who voluntarily participate in the split-face controlled study and provide written informed consent. Exclusion Criteria: * Having received systemic medications, dermabrasion, or laser therapy within the past 3 months; * Females who are pregnant, lactating, or planning to become pregnant; * Presence of severe systemic diseases; * Psychiatric disorders or impaired capacity for self-care; * Photosensitivity or having taken photosensitizing medications within the past month; * Atopic diathesis or history of severe allergic reactions; * History of skin exposure to intense sunlight within the past month; * History of keloid formation; * Presence of active skin tumors or infections; * Subjects allergic to rhGM-CSF gel or similar products; * Other subjects deemed ineligible for the study.

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Conditions

The condition(s) this trial relates to.

injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne scars - atrophic Wound healing

Contacts and locations

Locations

  • 1927-Nm Fractional Thulium Fiber Laser

    Xi'an, Shaanxi, 710004, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.