Can a 7-Day drug course wake up the immune system in critically ill children?
NCT ID NCT03769844
First seen May 08, 2026 · Last updated May 22, 2026 · Updated 2 times
Summary
This study tested a drug called GM-CSF in 75 children with sepsis who had organ failure and a weakened immune system (immunoparalysis). The goal was to see if a 7-day course of GM-CSF could restore their immune function. The researchers compared two doses and two ways of giving the drug (IV or injection) to find the best approach.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Benioff Children's Hospital/UCSF
San Francisco, California, 94158, United States
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Children's Hospital of Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Michigan
Detroit, Michigan, 48201, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15224, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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UCLA Mattel Children's Hospital
Los Angeles, California, 90095, United States
Conditions
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