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Blood protein may reveal who benefits from liver cancer immunotherapy

NCT ID NCT05263830

First seen Jan 06, 2026 · Last updated Jun 11, 2026 · Updated 33 times

Summary

This study is for adults with advanced liver cancer who are starting a common immunotherapy combination (Atezolizumab and Bevacizumab). Researchers want to see if levels of a protein called Glypican-3 in the blood can help predict how well the treatment works. About 240 participants will have their blood tested before treatment, at 3 weeks, and at 3 months. The goal is to find a simple way to identify which patients are most likely to benefit from this therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Service hépato-gastroentérologie, Hôpital la Pitié-Salpêtrière

    RECRUITING

    Paris, 75013, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma Simpson-Golabi-Behmel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.