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Simple amino acid may sharpen aging brains

NCT ID NCT07643675

Symptom relief Sponsor: Brenda Sarahí Beristain Lujano Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether taking 1,000 mg of glycine daily for six months could improve memory and thinking in older adults. Fifty-nine participants took the supplement, and researchers measured changes in a brain health marker and cognitive test scores. The goal was to see if this safe, affordable supplement could support healthy aging.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Glycine (dietary supplement)
What this could lead to
If it works, this could point toward a simple, safe supplement to help older adults maintain memory and thinking skills.
What could go wrong
This was a small, completed trial with only 59 participants, so results may not apply to everyone. The effects on cognition were measured with a screening test, not a full diagnostic tool.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

59 people

The number who actually took part.

Started

Dec 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: -Individuals across all nutritional statuses according to Body Mass Index (BMI): underweight, normal weight, overweight, and obesity. Exclusion Criteria: * Clinically relevant comorbidities (requiring patient hospitalization or a diagnosis of any infectious/contagious disease). * Consumption of polyphenol-based supplements or herbal blends within the two weeks prior to the study. * Mental incapacity. * Lack of willingness. * Language barriers that prevent adequate understanding or co-operation.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Cognitive Dysfunction Inflammation metabolic syndrome X

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Insulin resistance syndrome Older adults with cognitive decline

Contacts and locations

Locations

  • Escuela Superior de Medicina

    México, State of Mexico, 01710, Mexico

More trials for these conditions

Other studies related to the condition(s) this trial covers.