Brain fuel mystery: can glucagon change how we think?
NCT ID NCT07350512
First seen Jan 27, 2026 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This pilot study will test how the hormone glucagon affects brain activity and sugar use in 15 healthy adults. Participants receive an alanine infusion to raise glucagon levels, while researchers measure changes in blood sugar and cognitive function. The goal is to understand basic biology, not to treat any disease.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Department of Clinical Biochemistry, Copenhagen University Hospital - Bispebjerg and Frederiksberg
Copenhagen, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
alanine
What this could lead to
If successful, this could reveal how glucagon influences brain energy use and thinking, potentially guiding future research into metabolic brain disorders.
What could go wrong
This is a very small pilot study in healthy people, so results may not apply to patients. It only looks at short-term effects and does not test any treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.