Ultrasound study reveals stomach risks for patients on popular diabetes drugs
NCT ID NCT06003985
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study used a simple bedside ultrasound to check if patients taking GLP-1 agonist drugs (like Ozempic or Mounjaro) have more food or liquid in their stomach before surgery compared to those not on these drugs. Researchers enrolled 354 adults and looked for signs of delayed stomach emptying. The goal is to better understand if these medications increase the risk of complications during anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- GLP-1 agonists (semaglutide, dulaglutide, tirzepatide)
- What this could lead to
- If successful, this could help doctors know if GLP-1 drugs increase the risk of having food in the stomach during surgery, which could improve safety guidelines.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. It only measures stomach contents with ultrasound, so it cannot prove cause and effect or change practice on its own.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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354 people
The number who actually took part.
- Started
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Aug 2023
- Finished
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Feb 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will be comprised of patients scheduled for surgery at HSS who meet the following inclusion criteria and none of the exclusion criteria.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * GLP 1 patient group: any patient on GLP1 agonists that are dosed once per week (semaglutide, dulaglutide, tirzepatide), for all indications. * Control group (No GLP 1 patients): any patient not on GLP1 agonists that are dosed once per week, for all indications. Exclusion Criteria: * patient refusal to participate * patients with gastric bypass or any other gastric surgery * large hiatal hernia * patients with large ascites * patients on peritoneal dialysis * emergency surgery * pre-existing diagnosis of gastroparesis
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Albany Medical Center
Albany, New York, 12208, United States
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George Washington University Hospital
Washington D.C., District of Columbia, 20037, United States
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Hospital for Special Surgery
New York, New York, 10021, United States
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Mayo Clinic
Jacksonville, Florida, 32224, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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University Health Network
Toronto, Ontario, M5G 2C4, Canada
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University of Virginia
Charlottesville, Virginia, 22903, United States
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Weill Cornell Medicine
New York, New York, 10065, United States
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