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New hope for older lymphoma patients: gentler combo aims for better results

NCT ID NCT06765317

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 29 times

Summary

This study tests a new treatment plan for people aged 65 and older with diffuse large B-cell lymphoma (DLBCL) or related lymphomas. The treatment combines the standard chemotherapy (R-miniCHP) with three newer drugs (glofitamab, polatuzumab, and obinutuzumab) to see if it can improve response rates while causing fewer or milder side effects. About 42 participants will receive this therapy, and researchers will monitor how well the cancer shrinks or disappears.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.