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New vaccine trial offers hope for kids with Hard-to-Treat brain tumors

NCT ID NCT02358187

First seen Jan 10, 2026 · Last updated Apr 29, 2026 · Updated 19 times

Summary

This study tests a vaccine made from proteins found on glioma cells, combined with an immune booster, in children whose low-grade gliomas have not responded to at least two prior treatments. The goal is to see if the vaccine can shrink the tumor or keep it from growing. About 25 children who carry a specific immune marker (HLA-A2) will receive up to 8 initial vaccines, with extra doses possible for up to two years if the tumor responds.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Pittsburgh of UPMC

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.