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Could a pill replace insulin shots for tiny newborns?

NCT ID NCT05687500

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 29 times

Summary

This study tests whether an oral medicine called glibenclamide can control high blood sugar in very premature babies (born before 32 weeks and weighing under 1500 grams). The goal is to see if it can be used instead of insulin, which is the current standard treatment. The study includes 35 infants and focuses on keeping blood sugar levels stable without causing dangerously low blood sugar.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hopital Necker - Enfants malades

    Paris, 75015, France

Conditions

The condition(s) this trial relates to.

hypoglycemia Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.