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Two-Angle eye surgery aims to preserve future options for children with glaucoma

NCT ID NCT07830017

NEW Disease control Sponsor: Zagazig University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers compare two surgical approaches for primary congenital glaucoma, a rare eye condition in children that raises pressure inside the eye. One group receives a combined operation: nasal goniotomy plus temporal trabeculotomy. The other group receives temporal trabeculotomy alone. The trial measures whether the combined surgery lowers eye pressure more effectively while leaving the upper part of the eye untouched for possible future operations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eye surgery that combines nasal goniotomy with temporal trabeculotomy
What this could lead to
If the combined surgery works better, it could give children with congenital glaucoma better long-term pressure control while keeping future surgical options open.
What could go wrong
This is a small study of 21 children at one center, so results may not apply broadly. Eye surgery in children carries risks like infection, bleeding, or the pressure not dropping enough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

21 people

The number who actually took part.

Started

Feb 2024

Finished

Feb 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 day to 2 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Child with primary congenital glaucoma Exclusion Criteria: * associated ocular diseases other than glaucom * posterior segment congenital anomalies

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Conditions

The condition(s) this trial relates to.

congenital glaucoma glaucoma primary congenital glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Primary congenital glaucoma

Contacts and locations

Locations

  • Zagazig University

    Zagazig, Sharqia Province, 44511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.