Glaucoma supplement trial halted early – no clear results

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age of 40 to 80 years * Bilateral open angle glaucoma with reliable visual field defects (at least one eye with mean deviation (MD) between -4.00 to -10.00 decibels (dB) on Humphrey Visual Field 24-2. * Group 1 (Peripheral): meets 1 hodapp-parrish-anderson (HPA) criteria for defect (3 contiguous points depressed on the pattern standard deviation (PSD) p \<5%, one of which is depressed at p \<1% level), and does not meet below paracentral criteria for Group 2. * Group 2 (Central): at least 1 paracentral point repeatedly depressed at p\<1% on 24-2. Also meets the HAP criteria outlined above. * Visual acuity 20/40 or better in each eye * Intraocular Pressure (IOP) controlled at 2 measurements \>3 months * Clear media Exclusion Criteria: * Known bleeding disorder * History of epilepsy or on anti-seizure medication * Uncontrolled hypertension or diabetes * Uncontrolled IOP * Eye pathology leading to inaccurate IOP measurement * Visually significant retinal pathology affecting vision in past or active (such as diabetic retinopathy or age related macular degeneration) * Non-glaucomatous optic neuropathy * Visually significant cataract (worse then 2+ cataract, or what is determined visually clinically significant by physician) * History of ocular trauma * Selective laser trabeculoplasty or laser procedure within past 3 months * Cataract surgery within past 3 months * Incisional glaucoma surgery within 6 months * Current use of nitroglycerin * Current use of antiplatelet therapy besides aspirin (such as clopidogrel) or anticoagulation (such as warfarin) * Current use of systemic steroids or immunomodulating agents such as methotrexate. * Sensitivity or allergy to any ingredients in GlaucoCetin: Curcumin, L-Taurine, N-Acetyl Cysteine, Niacinamide, Ginkgo Biloba, Lipoic Acid, Citicoline, Grape Seed Extract, Green Tea Leaf Extract, Coenzyme Q10, Biotin, Natural Astaxanthin, flavonoid complex containing Fisetin, Quercetin, and Luteolin * Recent change in systemic medications or vitamins * Use of Biotin, Ginkgo Biloba, Citicoline within past 3 months (or any other Glaucocetin ingredients within 1 month) * Unreliable visual fields * Unwilling to take supplement or placebo for 6 months