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Gum study seeks age clues: kids vs teens

NCT ID NCT07607639

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at fluid from the gums of 80 people with gingivitis—half children aged 8-12, half young adults aged 15-24. Researchers will measure inflammation markers to see if they differ by age. The goal is to understand how gum disease develops during growth and puberty.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help explain how gum inflammation changes as kids grow up, possibly leading to better prevention or treatment for different ages.
What could go wrong
This is a small observational study, not a treatment trial. It only looks at biomarkers, so it won't directly improve gum health or provide a new therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited from the Pedodontics and Periodontology Clinics of Niğde Ömer Halisdemir University Faculty of Dentistry. The study population will consist of systemically healthy children and young adults diagnosed with gingivitis. Participants will be divided into two age-based groups: children aged 8-12 years and young adults aged 15-24 years. Individuals aged 13-14 years will be excluded due to being in a transitional pubertal stage associated with significant hormonal variability that may influence gingival inflammatory responses and confound biomarker levels. All participants will undergo clinical periodontal examination and gingival crevicular fluid sampling for biomarker analysis.

Ages

8 to 24 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals aged 8-12 years (child group) or 15-24 years (young adult group) 2. Clinical diagnosis of gingivitis 3. Presence of fully erupted tooth #31 with closed apex 4. Systemically healthy individuals 5. No history of periodontal treatment in the last 3 months 6. No antibiotic or anti-inflammatory drug use in the last 3 months 7. Good cooperation and willingness to participate 8. Written informed consent from participants or legal guardians (for minors) Exclusion Criteria: 1. Age 13-14 years (transitional pubertal period) 2. Presence of periodontitis or other periodontal diseases 3. Systemic, genetic, or immunological diseases 4. Acute oral infections or conditions requiring emergency treatment 5. Orthodontic appliances in the sampling region 6. Smokers 7. Pregnant or lactating individuals 8. Individuals with cognitive, psychological, or physical disabilities affecting cooperation 9. Inadequate eruption or incomplete root development of tooth #31 10. Refusal to participate or withdrawal of consent

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Niğde Ömer Halisdemir University Faculty of Dentistry

    RECRUITING

    Niğde, 51240, Turkey (Türkiye)

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