Could ginger and perilla replace acid pills for stomach trouble?
NCT ID NCT07655219
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a dietary supplement made from ginger and perilla (Dispepril®) can improve stomach symptoms in people with functional dyspepsia, a condition causing fullness, bloating, and pain after eating. 400 adults will be randomly assigned to take the supplement alone, the supplement plus a half-dose acid-reducing drug, or a full-dose acid-reducing drug for 14 days. The goal is to see if the supplement works as well as standard treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ginger and perilla extract supplement (Dispepril®)
- What this could lead to
- If it works, this could offer a natural alternative to acid-reducing drugs for people with chronic indigestion.
- What could go wrong
- This is a small, early-stage trial with only 14 days of treatment. The supplement may not work better than standard drugs, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 400 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female participants aged 18 to 65 years * Diagnosis of functional dyspepsia according to Rome IV criteria * Willingness and ability to provide written informed consent * Ability to follow study product administration instructions * Ability to attend scheduled study visits Exclusion Criteria: * Gastrectomy * Cancer * Use of NSAIDs, cholagogues, or tricyclic antidepressants within 30 days prior to enrollment * Helicobacter pylori positivity * Alcoholism or other substance abuse * Hepatic disease * Renal disease * History of hypersensitivity to formulation active ingredients or excipients * Pregnancy or breastfeeding * Participation in another clinical trial or completion of another clinical trial within 1 month prior to enrollment * Refusal or inability to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gastroenterology Centre
Salerno, Italy
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U.O.S.D. Digestive Endoscopy, Interventional and Emergency Unit
Montevarchi, Italy
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University of Rome Tor Vergata
Rome, Italy
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University of Urbino Carlo Bo
Urbino, Italy
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