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New hope for refractory lymphoma: Genotype-Guided cocktail targets resistant cancer

NCT ID NCT07493330

First seen Apr 13, 2026 · Last updated May 24, 2026 · Updated 5 times

Summary

This study tests a personalized treatment for people with a rare and aggressive blood cancer called peripheral T-cell lymphoma (PTCL) that did not respond to initial chemotherapy. Doctors will use genetic testing of the tumor to select a combination of drugs, including an experimental EZH2 inhibitor called zeprumetostat. The goal is to shrink or control the cancer, not to cure it. The trial involves 86 adults and is in early phases (1 and 2) to check safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Conditions

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