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Could a soy supplement sharpen memory and mood within hours?

NCT ID NCT07742514

Symptom relief Sponsor: University of Reading Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This trial tests whether two natural soy compounds, genistein and equol, can improve memory, thinking speed, and mood shortly after a single dose. Around 53 generally healthy adults will take either one of the supplements or a placebo, then complete a series of computer and paper tasks measuring verbal memory, spatial memory, attention, and mood. The goal is to see if these isoflavones offer a quick, safe cognitive lift in the hours after consumption.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Genistein and Equol, two soy-derived isoflavone supplements, taken as a single dose compared against a placebo (maltodextrin).
What this could lead to
If these soy compounds improve memory, attention, or mood after a single dose, they could point toward a simple dietary supplement for everyday cognitive support.
What could go wrong
This is a small, short-term study in healthy adults, so any effects may be modest or not lasting. Results from a single dose may not translate to long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

53 people

The number who actually took part.

Started

Nov 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Not currently undertaking medications including but not limited to Hormone Replacement Therapy * Generally Healthy Exclusion Criteria: * Participant (female) has not menstruated in \>12 months (post-menopausal). * Allergy to soy

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Conditions

The condition(s) this trial relates to.

mood disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognition MOOD

Contacts and locations

Locations

  • School of Psychology and Clinical Languages, University of Reading

    Reading, Berkshire, RG6 6AL, United Kingdom

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