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Nerve block eases knee pain and may improve joint awareness

NCT ID NCT06744842

Symptom relief Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a numbing injection around knee nerves (genicular nerve block) can reduce pain and improve quality of life and joint position sense in people with chronic knee osteoarthritis. 40 adults aged 55-75 with moderate knee arthritis took part. The goal was to see if the block helps with pain and the ability to sense knee position.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Dec 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of bilateral primary knee osteoarthritis according to ACR (American College of Rheumatology) criteria. * Age between 55 and 75 years. * Presence of knee osteoarthritis classified as Grade 2 or Grade 3 according to the Kellgren-Lawrence grading system on radiographs taken within the last year. * Knee pain lasting longer than 6 months. * Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, total score 48-96 Exclusion Criteria: * Severe knee trauma within the last 6 months. * History of surgical operation on the knee region. * Intra-articular steroid and/or hyaluronate injection into the knee joint within the last 6 months. * Physical therapy targeting the knee within the last 6 months. * Regular use of NSAIDs within the last 6 months. * Presence of acute synovitis. * Neurological deficits in the lower extremity. * Presence of an inflammatory disease. * Poor general health condition (e.g., heart failure, advanced asthma, history of malignancy). * Any endocrine disorder that may cause polyneuropathy.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Osteoarthritis

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Ankara, Çankaya, 06800, Turkey (Türkiye)

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