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Scientists hunt for hidden genes behind sudden infant death

NCT ID NCT06244433

Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the DNA of 650 infants who died suddenly and their parents to find genetic changes that may raise the risk of Sudden Infant Death Syndrome (SIDS). By comparing the genes of the baby and both parents, researchers hope to discover new genetic variants linked to these tragic events. The goal is to better understand why some infants die unexpectedly and, in the future, help identify babies at higher risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 650 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The population included will consist of infants who died in the context of SUDI and both their parents. These cases of SUDI will come from the French SUDI registry, which records all cases of SUDI occurring in children under 2 years of age throughout France via a network of referral centers for the management of SUDI.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Child Inclusion Criteria * Death of a child between 0 and 2 years of age due to sudden unexpected death in infant * Child included in the French SUDI registry with effective participation in the biocollection * Children who also meet the inclusion criteria for the BIOMINRISK-NEUROBIO (axis 2) and BIOMINRISK-RADIO-ANAT (axis 3) studies in the overall BIOMINRISK project. Parents Inclusion Criteria * Biological parents of the child included in the BIOMINRISK study * Parents who have both signed the consent form for blood collection and inclusion of their samples in the biocollection * parents beneficiaries of a social security or similar scheme Child Exclusion Criteria: * Presence of a known metabolic, genetic or syndromic pathology at the time of death Parents Exclusion Crtiteria: * Parent under guardianship * Presence of a known metabolic, genetic or syndromic pathology

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Conditions

The condition(s) this trial relates to.

Sudden Infant Death sudden unexpected infant death

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sudden infant death Sudden unexplained infant death

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    18 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AP-HM

    NOT_YET_RECRUITING

    Marseille, France

  • APHP - Hôpital Antoine Béclère

    RECRUITING

    Clamart, France

  • APHP - Hôpital Jean Verdier

    RECRUITING

    Bondy, France

  • CHRU Nancy

    RECRUITING

    Nancy, France

  • CHU Amiens

    RECRUITING

    Amiens, France

  • CHU Angers

    RECRUITING

    Angers, France

  • CHU Besançon

    RECRUITING

    Besançon, France

  • CHU Brest

    RECRUITING

    Brest, France

  • CHU Grenoble

    RECRUITING

    Grenoble, France

  • CHU Montpellier

    RECRUITING

    Montpellier, France

  • CHU Rouen

    RECRUITING

    Rouen, France

  • CHU Saint Etienne

    RECRUITING

    Saint-Etienne, France

  • CHU Toulouse

    RECRUITING

    Toulouse, France

  • CHU de Caen-Normandie

    NOT_YET_RECRUITING

    Caen, France

  • CHU de Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

  • Centre Hospitalier Sud Francilien

    NOT_YET_RECRUITING

    Corbeil-Essonnes, France

  • HCL

    RECRUITING

    Lyon, France

  • Nantes University Hospital

    RECRUITING

    Nantes, Loire-Atlantique, 44093, France

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