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Scientists hunt for gene clues to liver risk in kids

NCT ID NCT01862211

First seen Jan 03, 2026 · Last updated May 22, 2026 · Updated 18 times

Summary

This study looked at genes in children with alpha-1 antitrypsin deficiency, a condition that can cause liver disease. Researchers compared the DNA of children who had liver problems with those who did not, to find genetic markers that might predict severe liver damage. About 296 children and their family members took part, but no treatment or medication was given.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HP - Kremlin Bicêtre

    Le Kremlin-Bicêtre, France

  • AP-HP Hôpital Necker

    Paris, France

  • CH Saint Nazaire

    Saint-Nazaire, France

  • CHG Le HAVRE

    Le Havre, France

  • CHU Estaing

    Clermont-Ferrand, France

  • CHU d'Amiens - Hopital Nord

    Amiens, France

  • CHU de BESANCON

    Besançon, France

  • Centre de Pédiatrie Gatien de Clocheville

    Tours, France

  • Hopital Hautepierre

    Strasbourg, France

  • Hopital de la Timone

    Marseille, France

  • Hôpital Anne de Bretagne

    Rennes, France

  • Hôpital Brabois Enfants

    Nancy, France

  • Hôpital Charles Nicolle

    Rouen, France

  • Hôpital Couple Enfant

    La Tronche, France

  • Hôpital Femme Mère Enfant de Lyon

    Bron, France

  • Hôpital Jeanne de Flandre

    Lille, France

  • Hôpital Mère Enfant

    Nantes, France

  • Hôpital Nord

    Saint-Etienne, France

  • Hôpital Pellegrin

    Bordeaux, France

  • Hôpital des Enfants

    Toulouse, France

Conditions

Explore the condition pages connected to this study.