Your DNA may decide your Diet's success: a genetic test for weight loss?
NCT ID NCT07760870
First seen Aug 12, 2026 · Last updated Aug 14, 2026 · Updated 2 times
Summary
This trial is testing whether a genetic score can predict how much weight and body fat people lose on a 12-week low-energy, high-protein diet. Obese adults aged 18-40 will follow a personalized diet plan and receive counseling, while researchers track changes in weight, body composition, and blood markers. The goal is to see if genetics can help tailor diet advice for better results.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low-Energy High-Protein Diet
- What this could lead to
- If successful, this could lead to personalized diet recommendations based on genetics, improving weight loss outcomes for people with obesity.
- What could go wrong
- This is a small, early-stage study, and the genetic score may not reliably predict individual responses. Results may not apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 29 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult males or females aged 18 - 40 years. * Classified as obese with a Body Mass Index (BMI) of 27 - 35 kg/m² and a waist circumference of ≥90 cm for men and ≥80 cm for women. * Willing to adhere to the prescribed low-energy high-protein diet. * Willing to undergo anthropometric measurements, body composition analysis, lipid profile testing, and genetic variation screening. * Signed the written informed consent form. Exclusion Criteria: * Having chronic diseases that affect metabolism or body weight. * Diagnosed with chronic kidney disease (CKD). * Currently pregnant, lactating, or planning a pregnancy during the study period. * Currently participating in an intensive weight loss program or receiving pharmacological therapy for weight loss within the last 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Integrated Health Science Building, Faculty of Health Sciences
Banyumas, Central Java, 53122, Indonesia
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