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Gene therapy offers hope for children with rare movement disorder

NCT ID NCT06432140

First seen Apr 06, 2026 · Last updated May 23, 2026 · Updated 7 times

Summary

This trial tests a gene therapy called VGN-R09b in 13 children with severe AADC deficiency, a rare genetic disorder that causes severe movement problems. The therapy is injected directly into a brain region to help restore missing enzyme activity. The study checks safety and whether children can achieve motor milestones like head control and walking.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai

    Shanghai, Shanghai Municipality, 200120, China

Conditions

Explore the condition pages connected to this study.