Gene therapy injection shows promise for rare childhood movement disorder

NCT ID NCT06432140

First seen Apr 06, 2026 · Last updated May 03, 2026 · Updated 5 times

Summary

This trial tests a gene therapy called VGN-R09b for children aged 1.5 to 8 years with severe AADC deficiency, a rare genetic disorder that severely limits movement. The treatment is injected directly into a brain region called the putamen. The study aims to see if it is safe and can help children achieve motor milestones like head control and walking. 13 children are enrolled.

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Contacts and locations

Locations

  • Shanghai

    Shanghai, Shanghai Municipality, 200120, China

Conditions

Explore the condition pages connected to this study.