New gene therapy attacks deadly brain tumors from two sides
NCT ID NCT07346144
First seen Jan 17, 2026 · Last updated May 23, 2026 · Updated 20 times
Summary
This trial tests a new gene therapy called TGX-007 for people with a fast-growing brain cancer called glioblastoma. The therapy uses a harmless virus to deliver two special instructions into the tumor: one helps a common antiviral drug kill cancer cells, and the other wakes up the immune system to attack the tumor. About 68 adults aged 18-70 with newly diagnosed or returning glioblastoma will receive a single injection of TGX-007 directly into the tumor, followed by a short course of an oral antiviral drug, before standard surgery. The study aims to find the safest and most effective dose and to see if it helps people live longer.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ohio State University Hospital
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, United Kingdom
Contact Email: •••••@•••••
Conditions
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