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First-Ever vagus nerve gene injection aims to tame rare nerve disease

NCT ID NCT07543991

First seen Apr 22, 2026 · Last updated May 01, 2026 · Updated 3 times

Summary

This early-stage trial tests a gene therapy injected directly into the left vagus nerve for people with giant axonal neuropathy (GAN), a rare and fatal nerve disease. Only 4 participants who previously received a spinal injection of the same therapy are eligible. The main goal is to check safety, with a secondary focus on whether it can stabilize or improve symptoms of the autonomic nervous system.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Health

    RECRUITING

    Dallas, Texas, 75235, United States

Conditions

Explore the condition pages connected to this study.