First-Ever vagus nerve gene injection targets fatal childhood nerve disease
NCT ID NCT07543991
First seen Apr 22, 2026 · Last updated Apr 28, 2026 · Updated 2 times
Summary
This early-stage trial tests a gene therapy injected directly into the left vagus nerve for people with giant axonal neuropathy (GAN), a rare, fatal nerve disease that affects movement, breathing, and automatic body functions. The study enrolls 4 participants who have already received a prior gene therapy injection into the spine. The main goal is to check safety, and researchers will also watch for improvements in automatic nerve symptoms like digestion and heart rate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Children's Health
RECRUITINGDallas, Texas, 75235, United States
Conditions
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