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New gene therapy aims to restore saliva in cancer survivors

NCT ID NCT02446249

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 22 times

Summary

This study tests a single dose of gene therapy injected into a saliva gland to see if it can safely increase saliva production in people with dry mouth from past head and neck cancer radiation. About 17 adults will take part, and they will be followed for three years. The main goal is to check safety, but researchers will also look for signs that the treatment helps with dry mouth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.