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Experimental gene therapy for DMD hits antibody barrier

NCT ID NCT06241950

First seen Nov 20, 2025 · Last updated May 22, 2026 · Updated 24 times

Summary

This study tested a gene therapy (delandistrogene moxeparvovec) combined with a drug called imlifidase to help patients with Duchenne muscular dystrophy who have antibodies that could block the therapy. Only 5 participants were planned, and the study was terminated early. The goal was to see if the treatment was safe and could produce dystrophin protein in muscle.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Sant Joan de Déu

    Barcelona, 08950, Spain

Conditions

Explore the condition pages connected to this study.