Experimental gene therapy for DMD hits antibody barrier – study halted
NCT ID NCT06241950
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a gene therapy (delandistrogene moxeparvovec) combined with a drug called imlifidase to see if it could safely deliver the therapy to boys with Duchenne muscular dystrophy who had antibodies that might block the treatment. Only 5 participants were planned, but the study was terminated early. The goal was to measure safety and how much dystrophin protein was produced in muscle.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Sant Joan de Déu
Barcelona, 08950, Spain
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Other studies related to the condition(s) this trial covers.
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