New gene therapy targets rare, aggressive ALS
NCT ID NCT06100276
First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 28 times
Summary
This study tests a gene therapy called AMT-162 in 20 adults with a specific genetic form of ALS (SOD1-ALS). The treatment is given as a single injection into the spinal fluid. The main goal is to check safety and tolerability, while also looking for early signs that it might slow the disease. Participants must have a confirmed SOD1 gene mutation and still have at least moderate physical function.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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Barrow Neurological Institute
Phoenix, Arizona, 85013, United States
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California Pacific Medical Center
San Francisco, California, 94109, United States
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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Massachusetts General Hospital, Sean M. Healey and AMG Center for ALS Research
Boston, Massachusetts, 02114, United States
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Mayo Clinic Florida
Jacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States
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Norrlands Universitetssjukhus
Umeå, Vasterbottens Ian, Sweden
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Northwestern University Feinberg School of Medicine
Chicago, Illinois, 60611, United States
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University of California Irvine
Irvine, California, 92697, United States
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University of Kansas Medical Center
Fairway, Kansas, 66205, United States
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University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania, 19104, United States
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Winship Cancer Institute of Emory University
Atlanta, Georgia, 30322, United States
Conditions
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