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New chemo combo shows promise for Tough-to-Treat brain tumors in kids

NCT ID NCT01270724

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times

Summary

This study tested a new chemotherapy combination (GemPOx) followed by a single round of very high-dose chemotherapy and a stem cell transplant in 10 patients with recurrent or progressive brain germ cell tumors. The goal was to see if this approach could shrink or control the tumors. While the treatment aims to manage the disease, it does not eliminate the need for ongoing monitoring and potential future therapies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • The Ohio State University Wexner Medical Center_The James Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.