Stomach bug subtypes may raise cancer risk – study to track 3,000 people
NCT ID NCT06896370
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 3,000 adults aged 40 and older who carry Helicobacter pylori, a common stomach bug. Researchers want to see if people with certain high-risk subtypes of the bacteria develop stomach cancer more often than those with other subtypes or no infection. Participants will have regular check-ups and stomach exams over 3 to 10 years. No treatment is given—this is purely an observation to better understand cancer risk.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify which H. pylori carriers are at highest risk for stomach cancer, enabling targeted screening.
- What could go wrong
- This is an observational study, not a treatment trial. It only tracks risk and cannot prove cause. Results may take years and may not change current screening guidelines.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 3,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Dec 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects were recruited from communities in Tongling, Anhui Province.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria : 1. Age ≥ 40 years, gender is not limited. 2. Able and willing to provide informed consent and willing to undergo baseline and follow-up examinations. Exclusion Criteria: 1. A history of diagnosed gastric cancer or other malignant tumors of the digestive tract. 2. Comorbid severe underlying conditions (e.g., severe cardiopulmonary insufficiency, liver or renal failure, etc.) that are likely to result in a short life expectancy or render long-term follow-up impractical. 3. Severe mental illness or incapacity to participate in the study due to lack of civil behavior. 4. Pregnant or breastfeeding women. 5. Other conditions that the investigator deems inappropriate for participation in the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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People's Hospital of Tongling City
RECRUITINGTongling, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood test may reveal how well stomach cancer treatment works
- Beyond h. pylori: a hidden stomach bacteria may influence cancer risk
- Shorter h. pylori treatment put to the test: 10 days vs. 14 days
- Can a simple blood test predict leukemia risk after cancer therapy?
- When to treat? new trial aims to optimize therapy for oligometastatic esophageal and gastric cancer
- Battle of the bacteria: which h. pylori treatment wins?