Can a simple anesthesia tweak keep lungs clearer after surgery?
NCT ID NCT07753278
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial is testing whether using a lower or higher flow of fresh gas during general anesthesia affects how well the lungs recover after laparoscopic gallbladder removal. About 120 adults having this surgery will be randomly assigned to receive either low-flow (0.5 L/min) or high-flow (4 L/min) anesthesia. The researchers will use lung ultrasound 30 minutes after the breathing tube is removed to measure lung aeration and check for collapse (atelectasis). The goal is to see if one approach leads to better lung function after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Low or high fresh gas flow during general anesthesia
- What this could lead to
- If low-flow anesthesia proves better, it could reduce lung complications after surgery and improve recovery for patients undergoing laparoscopic procedures.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to all surgeries or patients. The difference between gas flows might be too small to matter clinically.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. * American Society of Anesthesiologists (ASA) physical status I-II. * Scheduled for elective laparoscopic cholecystectomy under general anesthesia. * Able and willing to provide written informed consent. Exclusion Criteria: * Refusal to participate in the study. * History of chronic respiratory disease, including severe asthma, chronic obstructive pulmonary disease (COPD), or bronchiolitis. * History of alcohol or substance abuse. * Intraoperative airway or respiratory complications during endotracheal intubation or surgery. * Life-threatening postoperative complications. * Patients with ASA physical status III or higher.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Adıyaman Training and Research Hospital
Adıyaman, 02100, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Gentle lung breathing during bypass may prevent Post-Surgery collapse
- Lung imaging could supercharge Post-Surgery breathing exercises
- Beeping breathing aids could cut Post-Surgery lung risks
- High-Flow oxygen may shield lungs after keyhole surgery
- Timing of lung maneuver may reduce surgery complications