Can a video game rewire the brain to ease PTSD?
NCT ID NCT05313334
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 36 times
Summary
This pilot study tested a digital training task called GAMBIT in 50 adults with PTSD. The goal was to see if playing this brain-training game could improve brain circuit flexibility and reduce PTSD symptoms. The study was terminated early, so the findings are limited.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GAMBIT Task (a digital inhibitory control training game)
What this could lead to
If successful, this could point toward a new, non-drug approach to help people with PTSD by training their brain's control circuits.
What could go wrong
This was a very small, early pilot study that was terminated before completion, so results are limited and may not be reliable. The intervention is a simple computer task, not a proven treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.