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Can a simple blood test flag heart rhythm trouble after bypass surgery?

NCT ID NCT06768528

Diagnosis Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers are studying whether high levels of a blood protein called Galectin-3 can predict which patients will develop an irregular heartbeat after coronary artery bypass grafting. About 90 adults scheduled for this surgery will give a blood sample before the operation and be followed for a year. The goal is to learn whether Galectin-3 levels relate to post-operative atrial fibrillation and other complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a blood test for the protein Galectin-3
What this could lead to
If the protein tracks with heart rhythm problems after bypass surgery, doctors could one day use a simple blood test to flag high-risk patients and watch them more closely.
What could go wrong
This is a small observational study of 90 people, so it can show a link but not prove cause and effect. A single protein may not predict complications well enough to change care on its own.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Single-center cohort study with patients admitted for coronary artery bypass graft (CABG) surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing coronary artery bypass graft surgery Exclusion Criteria: * Inability to sign the free and informed consent form * Renal dysfunction with estimated glomerular filtration rate less than 30ml / min / 1.73m² or dialysis therapy * Moderate to severe left ventricular dysfunction (ejection fraction \< 40%) * Patients with previous atrial fibrillation * Pregnancy * Concomitant valve surgery

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Conditions

The condition(s) this trial relates to.

atrial fibrillation cardiovascular disorder Postpericardiotomy Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Post-operative atrial fibrillation Post-pericardiotomy syndrome

Contacts and locations

Locations

  • Instituto do Coração - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo

    São Paulo, São Paulo, 05403000, Brazil

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