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New blood test could spot liver cancer sooner

NCT ID NCT07319299

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study is testing whether a new blood test score, called GAAD, can detect liver cancer earlier in people with chronic liver disease. The GAAD score combines a person's gender, age, and two blood markers (AFP and PIVKA-II). Researchers will compare the GAAD score to standard ultrasound and AFP tests in 2,100 participants over 24 months. The goal is to see if the GAAD score improves detection and reduces false alarms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Faculty of Medicine Siriraj Hospital

    Bangkoknoi, Bangkok, 10700, Thailand

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GAAD score (blood test combining gender, age, AFP, and PIVKA-II)

What this could lead to

If successful, the GAAD score could become a standard, more accurate blood test to catch liver cancer early in people with chronic liver disease.

What could go wrong

This is a diagnostic study, not a treatment. The GAAD score may not prove significantly better than current methods, and results may not apply outside the specific patient group studied.

Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.