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New radiation schedule could cut treatment time for throat cancer patients

NCT ID NCT06080503

First seen Dec 10, 2025 · Last updated Jun 22, 2026 · Updated 29 times

Summary

This phase II trial compares a new, shorter radiation schedule (LT-SABR, given over 1-2 weeks) to standard radiation (over 5-6 weeks) for early-stage laryngeal cancer. The goal is to see if the shorter schedule causes fewer severe side effects in the first 3 months. About 67 adults with stage 0-II glottic laryngeal cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Texas Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy (LT-SABR or IMRT)

What this could lead to

If successful, this could offer a shorter, more convenient radiation schedule with fewer acute side effects for people with early-stage laryngeal cancer.

What could go wrong

This is a small, early-phase study (67 participants) comparing two radiation approaches, so results may not apply broadly. The higher-dose schedule could also increase long-term risks.

Conditions

The condition(s) this trial relates to.

glottis squamous cell carcinoma laryngeal carcinoma laryngeal disorder laryngeal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.