Exercise program may boost natural pain relief in chronic back pain sufferers
NCT ID NCT07347457
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at whether a 4-week functional rehabilitation program, focused on supervised exercise, can improve exercise-induced hypoalgesia — the natural pain relief that happens after physical activity — in people with chronic low back pain. Researchers will measure pain thresholds before and after exercise in 51 participants enrolled in the program. The goal is to see if regular exercise training can make exercise more effective at reducing pain, which could help people stay active.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Functional rehabilitation program (supervised exercise sessions)
- What this could lead to
- If it works, this could point toward a way to make exercise more effective at reducing pain in people with chronic low back pain.
- What could go wrong
- This is a small, early exploratory study with only 51 participants, so results may not apply to everyone. It also does not test a new drug or treatment, just a program already in use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 51 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Voluntary participant * Able to provide written informed consent * Aged between 18 and 60 years * Diagnosed with chronic low back pain, defined as persistent low back pain for at least three months * Enrolled in the functional rehabilitation program at Les Peupliers Clinic * Affiliated with a health insurance system Exclusion Criteria: * Presence of a contraindication to physical activity * Presence of a severe cardiovascular, neurological, or psychiatric condition * Pregnant or breastfeeding women * History of alcohol and/or drug addiction * Individuals under legal guardianship or curatorship * Individuals in an emergency situation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Clinique les Peupliers
Villeneuve-d'Ascq, 59491, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Back muscles hold clues for treating recurrent low back pain
- Skip the GP? physiotherapy first for back pain put to the test
- Can yoga ease back pain when recovery looks unlikely?
- Can a second injection target the source of stubborn back pain?
- Can releasing a deep back muscle ease pain and help you breathe better?