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New sickle cell drug shows early promise in safety trial

NCT ID NCT05169580

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This early-stage study tested a new drug called Pociredir (FTX-6058) in 45 adults with sickle cell disease. The main goal was to check if the drug is safe and how the body processes it. Researchers also looked at whether it could increase fetal hemoglobin, which may help reduce sickle cell complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Barau Dikko Teaching Hospital

    Kaduna, 800125, Nigeria

  • Boston Medical Center

    Boston, Massachusetts, 02118, United States

  • Charlotte Maxeke Johannesburg Academic Hospital

    Johannesburg, 2193, South Africa

  • Eastern Carolina University

    Greenville, North Carolina, 27834, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Jacobi Medical Center

    The Bronx, New York, 10461, United States

  • Lynn Health Science Institute

    Oklahoma City, Oklahoma, 73112, United States

  • National Hospital, Abuja

    Abuja, 900247, Nigeria

  • Our Lady of the Lake Hospital

    Baton Rouge, Louisiana, 70808, United States

  • Queens Hospital Cancer Center

    Jamaica, New York, 11432, United States

  • Sonar Research Center

    Atlanta, Georgia, 30315, United States

  • University of Arkansas for Medical Sciences (UAMS)

    Little Rock, Arkansas, 72205, United States

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

  • University of Ibadan

    Ibadan, 200212, Nigeria

  • University of Illinois Chicago

    Chicago, Illinois, 60612, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

  • University of Texas Houston

    Houston, Texas, 77030, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.