New hope for FSHD: antibody drug aims to slow muscle loss
NCT ID NCT05548556
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 19 times
Summary
This study tests an experimental antibody called RO7204239 in 51 adults with facioscapulohumeral muscular dystrophy (FSHD), a genetic disease that causes progressive muscle weakness. The drug blocks a protein that limits muscle growth, with the goal of preserving or increasing muscle volume. Participants receive either the drug or a placebo, and researchers measure changes in muscle size and safety over time.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Asst Grande Ospedale Metropolitano Niguarda
Milan, Lombardy, 20162, Italy
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Kennedy Krieger Institute
Baltimore, Maryland, 21205, United States
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National Hospital for Neurology and Neurosurgery,
London, WC1N 3BG, United Kingdom
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Policlinico Universitario Agostino Gemelli
Rome, Lazio, 00168, Italy
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Regents of the University of Colorado
Aurora, Colorado, 80045, United States
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Rigshospitalet
København Ø, 2100, Denmark
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Royal Victoria Infirmary
Newcastle upon Tyne, NE1 4LP, United Kingdom
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University of Irvine Medical Center (UCIMC)
Orange, California, 92868, United States
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University of Kansas Medical Center
Fairway, Kansas, 66205, United States
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Virginia Commonwealth University Medical Center
Richmond, Virginia, 23298-0599, United States
Conditions
Explore the condition pages connected to this study.