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Can a sugar in your drink quietly weaken your Gut's defenses?

NCT ID NCT07757347

Knowledge-focused Sponsor: University of Vienna Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial asks whether consuming low doses of fructose, a common sugar, affects the intestinal barrier and immune response in healthy adults. Participants follow a standardized diet for three days, then receive a drink with either fructose or glucose. Researchers will measure markers of gut permeability and immune cell activity to see if fructose has a distinct effect.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Fructose
What this could lead to
If fructose is shown to affect gut permeability and immune markers, it could inform dietary advice for maintaining gut health.
What could go wrong
This is a small, early-stage study in healthy people, so results may not apply to the general population or those with gut conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * all gender, healthy collective ≥ 18 years old Exclusion Criteria: * Chronic inflammatory diseases of the gastrointestinal tract * Metabolic diseases or taking medication to treat metabolic diseases * Fructose malabsorption * Hereditary fructose intolerance * Food intolerances and/or allergies, as well as food allergies that require special dietary interventions * Special diets, such as vegetarian/vegan diets * Unstable body weight within the last 6 months (fluctuations of \> 5%) * BMI \< 19 kg/m2 \& \> 29,9 kg/m2 * Bariatric surgery * Smoking * Liver diseases * Renal insufficiency * Rheumatoid arthritis * COPD with ≥ 2 exacerbations per year * Chronic pancreatitis or recurrent acute pancreatitis * Alcohol consumption above 10 g/d for women and above 20 g/d for men * Pregnancy and breastfeeding * Viral or bacterial infections that occurred no longer than 3 weeks ago

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Immune response Intestinal permeability

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Vienna

    RECRUITING

    Vienna, 1090, Austria

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