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A simple ECG angle might predict the Heart's own bypass system

NCT ID NCT07743437

Diagnosis Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study explores whether the frontal QRS-T angle, measured from a standard 12-lead ECG, can serve as a marker for collateral circulation in patients with chronic total occlusion (CTO) — a condition where a coronary artery is completely blocked. Researchers will compare ECG readings with coronary angiography results, which directly visualize these collateral vessels, in 100 patients. The goal is to see if a non-invasive ECG measurement could help assess the heart's natural bypass network.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
12-lead electrocardiogram (ECG) and coronary angiography
What this could lead to
If the frontal QRS-T angle reliably indicates collateral circulation, doctors might use a simple ECG to gauge heart health in CTO patients, potentially reducing the need for invasive angiography.
What could go wrong
This is an observational study with a modest sample size, so the findings may not apply to all patients. The ECG marker might not be accurate enough to replace angiography in clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients presenting to the cardiology department who have experienced stable angina for a minimum of three months and are subsequently diagnosed with a chronic total occlusion (CTO) in at least one coronary artery during routine diagnostic coronary angiography.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing diagnostic coronary angiography due to stable angina persisting for a minimum duration of three months. * Patients diagnosed with total occlusion in at least one coronary artery, assessed to have chronic total occlusion (CTO) based on clinical and angiographic findings. Exclusion Criteria: * Patients presenting with malignancies, atrial fibrillation, connective tissue disorders, hepatic failure, or renal failure. * A documented history of cardiac pacemaker implantation, prior bypass surgeries, or surgical valve replacements. * Congenital heart anomalies. * Patients receiving pharmacological interventions that affect ventricular repolarization (other than beta-adrenergic antagonists). * Individuals exhibiting abnormal electrolyte levels at the time of admission.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic total occlusion (CTO) Frontal QRS-T angle

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AssiutU

    Asyut, Egypt

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