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Brain wave study tests three drugs in fragile x adults

NCT ID NCT05418049

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 17 times

Summary

This study looks at how single doses of baclofen, roflumilast, and memantine affect brain activity and behavior in 45 adults with Fragile X syndrome. Participants take one dose of each drug or a placebo on separate days. The goal is to measure changes in brain waves and clinical symptoms, not to cure the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.