Brain wave study tests three drugs for fragile x

NCT ID NCT05418049

First seen Jan 05, 2026 · Last updated Apr 28, 2026 · Updated 16 times

Summary

This study looks at how single doses of baclofen, roflumilast, and memantine affect brain activity and behavior in 45 adults with Fragile X Syndrome. Participants take each drug or a placebo on separate days, and researchers measure changes in brain waves and clinical symptoms. The goal is to understand how these drugs impact the condition, not to provide a treatment.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.