Ovarian cancer test accuracy under review in 1,000 women
NCT ID NCT07539844
First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 3 times
Summary
This study looks at how well different labs agree when testing for a protein called FRa in stored tumor samples from women with ovarian cancer. About 1,000 women's archived tissue will be tested, but no new treatments or visits are needed. The goal is to improve consistency of FRa testing, which may help guide future treatment decisions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population is surgical or biopsy sample from an adult female with tumoral High Grade Serous Ovarian Cancer.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Surgical or biopsy samples (Formalin Fixed Paraffin Embedded \[FFPE\]) with tumoral High Grade Serous Ovarian Cancer (HGSOC) material allowing the sectioning of serial slides for all the analyses. * Archival specimens should not be older than 5 years in order to control quality of the samples. * Specimens containing a minimum of 100 viable tumor cells. Exclusion Criteria: * Surgical or biopsy samples (FFPE) with insufficient quantity or quality (sampled more than 5 years ago and/or with less 100 viable tumor cells per section). * Tissue obtained following treatment with Mirvetuximab soravtansine or any other FRa targeted therapy. * Tissue obtained through fine needle aspirations or liquid specimens, or ascites
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
12 sites in 5 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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A.C. Camargo Cancer Center - Rua Professor Antonio Prudente /ID# 280407
RECRUITINGSão Paulo, São Paulo, 01509-900, Brazil
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Biomakers /ID# 280318
RECRUITINGBuenos Aires, Buenos Aires, 1119, Argentina
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Brazil - Generic Institution /ID# 287000
RECRUITINGSão Paulo, Brazil
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Fundacion Para La Investigacion Clinica Y Molecular Aplicada Del Cancer - Ficmac /ID# 282327
RECRUITINGBogotá, Bogota D.C., 110111, Colombia
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Fundacion Valle Del Lili /ID# 280794
RECRUITINGCali, Valle del Cauca Department, 760016, Colombia
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Hospital Italiano de Buenos Aires /ID# 280315
RECRUITINGBuenos Aires, Buenos Aires, 1181, Argentina
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Instituto Alexander Fleming /ID# 281479
RECRUITINGCiudad Autonoma de Buenos Aire, Buenos Aires F.D., 1426, Argentina
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Instituto Nacional De Cancerologia /ID# 282312
RECRUITINGBogota, Cundinamarca, 110411, Colombia
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Mexico - Generic Institution /ID# 281927
RECRUITINGMexico City, Mexico
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Mexico - Generic Institution /ID# 281928
RECRUITINGMexico City, Mexico
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Mexico - Generic Institution /ID# 281930
RECRUITINGMexico City, Mexico
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Toronto General Hospital-University Health Network /ID# 282521
RECRUITINGToronto, Ontario, M5G 2C4, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can MRI and computer models predict how well cancer drugs reach tumors?
- Can a Patient's own immune cells fight ovarian cancer?
- Ovarian Cancer's spread: scientists probe abdominal fluid for clues
- New PET tracer aims to light up hidden cancer targets
- Mapping the DNA test that decides who gets PARP inhibitors
- Cervical smear DNA may reveal ovarian cancer years before symptoms